Work

Temporal patterns of liver and adipose lipase abundance across the periparturient period in multiparous Holstein dairy cows

Year: 2024

Type: article

Abstract: ) was used as a cowside indicator of successful induction and was achieved in CTL (n = 2) and KIP (n = 12) cows. Both adipose and liver abhydrolase domain-containing protein 5 and adipose triglyceride lipase (ATGL) differed across DRTC, as did liver perilipin 1. Hepatic mature and immature carbohydrate response element binding protein, and sterol regulatory binding protein 1c, varied or tended to vary across DRTC × treatment. Neither adipose nor liver hormone sensitive lipase (HSL) were responsive to treatment or varied across DRTC, but adipose HSL was positively associated with nonesterified fatty acids at +1 DRTC. Adipose and liver ATGL was associated with liver triglycerides across all DRTC. Patterns of adipose HSL and ATGL abundance did not explain the increase in nonesterified fatty acids observed at +1 DRTC in this study. Future investigation of lipase abundance in other adipose tissue depots is still needed to better explain regulation during this time. Bovine fatty liver development and recovery appears to be contingent upon liver PNPLA3 abundance, rather than liver ATGL.

Source: JDS Communications

DOI: 10.3168/jdsc.2024-0613

Authors: S.J. Kendall, H.T. Holdorf, R.S. Pralle, H.M. White

Institutions: University of Wisconsin–Madison, University of Wisconsin–Platteville

Language: English

Topic: Reproductive Physiology in Livestock

Subfield: Agronomy and Crop Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,310