Work

Unlocking the potential of cultivated meat through cell line engineering

Year: 2024

Type: article

Abstract: Cultivated meat has the potential to revolutionize food production, but its progress is hindered by fundamental shortcomings of mammalian cells with respect to industrial-scale bioprocesses. Here, we discuss the essential role of cell line engineering in overcoming these limitations, highlighting the balance between the benefits of enhanced cellular traits and the associated regulatory and consumer acceptance challenges. We believe that careful selection of cell engineering strategies, including both genetic and non-genetic modifications, can address this trade-off and is essential to advancing the field.

Source: iScience

DOI: 10.1016/j.isci.2024.110877

Authors: Camilo Riquelme-Guzmán, Andrew J. Stout, David L. Kaplan, Joshua E. Flack

Institutions: Tufts University, Delft University of Technology

Language: English

Topic: Viral Infectious Diseases and Gene Expression in Insects

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,150

Funder: U.S. Department of Agriculture