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Radiation-Induced Angiosarcoma Arising in Bilateral Breast: A Case Report

Year: 2024

Type: article

Abstract: Radiation-induced angiosarcoma is a highly aggressive malignancy. We encountered a case of angiosarcoma arising in the bilateral breast seven years after partial mastectomy and the last radiation therapy. As recommended, wide resection with skin grafting was performed to ensure negative surgical margins. After surgery, taxane-based chemotherapy was administered. However, adjuvant chemotherapy was discontinued because of drug-induced institutional pneumonia. Eighteen months postoperatively, angiosarcoma recurred in subcutaneous, lymph nodes, lungs, and bones. The disease progressed too rapidly, and the patient died two months after recurrence.

Source: Cureus

DOI: 10.7759/cureus.68782

Authors: Wakako Tsuji, Katsuhiro Yoshikawa, Fumie Fujisawa, Chikako Yamauchi, Akihiko Sugimoto

Institution: Shiga Medical Center

Language: English

Topic: Vascular Tumors and Angiosarcomas

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402312736