Work

Release of Copper / Magnesium Ions from Hydroxyapatite-Based Fiber Scaffolds Hasten Bone Healing and Regeneration

Year: 2024

Type: article

Abstract: Releasing inorganic ions from Ca/P biomaterials could provide an alternative approach to using growth factors to improve bone healing. Two types of hydroxyapatite HA fiber scaffolds, copper-doped (CuHA) and magnesium-doped (MgHA), were fabricated by using the sol-gel method. Two types of scaffolds were immersed in simulated body fluid SPF (i,e, Phosphate Buffered Saline PBS) for 30 days. The results after immersions indicated the amount of Cu and Mg ions released from scaffolds. A low amount of Mg and Cu ions could improve vascular endothelial growth factor (VEGF) and angiogenesis around bone, thus can hasten bone healing and regeneration.

Source: Journal of Techniques

DOI: 10.51173/jt.v6i3.2567

Authors: Adil Elrayah, Jie Weng, Dongqin Xiao, Azher S Barrak

Institutions: Karary University, Southwest Jiaotong University, North Sichuan Medical University, Nanchong Central Hospital

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Natural Science Foundation of China