Individualized tacrolimus therapy: Insights from CYP3A5 polymorphisms and intestinal metabolism
Year: 2024
Type: article
Study design: Case Report
Abstract: CYP3A4 and CYP3A5 are the most abundant and important enzymes of the CYP3A subfamily, distributed in the liver, intestinal mucosa and kidney, and involved in tacrolimus metabolism. Here, we report a case of tacrolimus dosage refractoriness due to a genetic polymorphism of
Source: Clinical Case Reports
DOI: 10.1002/ccr3.9416
Authors: Mizuki Mishima, Tomohisa Yabe, Takaya Kondo, Keiji Fujimoto, Ryoji Takata, Hitoshi Yokoyama, Yo Niida, Tatsuro Tanaka, Katsuhito Miyazawa, Kengo Furuichi
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,730
OpenAlex ID: W4402322664