bio2Byte Tools deployment as a Python package and Galaxy tool to predict protein biophysical properties
Year: 2024
Type: software-paper
Abstract: SUMMARY: We introduce a unified Python package for the prediction of protein biophysical properties, streamlining previous tools developed by the Bio2Byte research group. This suite facilitates comprehensive assessments of protein characteristics, incorporating predictors for backbone and sidechain dynamics, local secondary structure propensities, early folding, long disorder, beta-sheet aggregation, and fused in sarcoma (FUS)-like phase separation. Our package significantly eases the integration and execution of these tools, enhancing accessibility for both computational and experimental researchers. AVAILABILITY AND IMPLEMENTATION: The suite is available on the Python Package Index (PyPI): https://pypi.org/project/b2bTools/ and Bioconda: https://bioconda.github.io/recipes/b2btools/README.html for Linux and macOS systems, with Docker images hosted on Biocontainers: https://quay.io/repository/biocontainers/b2btools?tab=tags&tag=latest and Docker Hub: https://hub.docker.com/u/bio2byte. Online deployments are available on Galaxy Europe: https://usegalaxy.eu/root?tool_id=b2btools_single_sequence and our online server: https://bio2byte.be/b2btools/. The source code can be found at https://bitbucket.org/bio2byte/b2btools_releases.
Source: Bioinformatics
Authors: Jose Gavalda-Garcia, Adrián Díaz, Wim Vranken
Institutions: Université Libre de Bruxelles, Vrije Universiteit Brussel
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $4,188
Awards: FoldMod: The role of local amino acid interactions in protein folding, fold stability and the location of post-translational modifications., Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics., G434337789, ELIXIR Infrastructure for Data and Services to strengthen Life-Sciences Research in Flanders
OpenAlex ID: W4402326455