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Thymoma with recurrent opportunistic infections—a case report

Year: 2024

Type: article

Abstract: Good's syndrome (GS) is a rare adult-onset thymoma associated with acquired combined B-cell and T-cell immunodeficiency. It has similarities with Common variable immunodeficiency (CVID) in terms of hypogammaglobulinemia and significant risk of invasive bacterial and opportunistic infections. We still have a long way to go in understanding the pathogenesis of Good's syndrome. Here, we describe a case of a middle-aged female with thymoma and recurrent opportunistic infections. Clinico-laboratory evaluation led to a diagnosis of GS and she showed good response to intravenous immunoglobulin. Clinicians should be aware that thymoma can precede the onset of immunodeficiency.

Source: Oxford Medical Case Reports

DOI: 10.1093/omcr/omae102

Authors: Sri Lasya Karjala, Satya Prasad Namala, Phani Krishna Machiraju, Prabu Pandurangan

Institutions: Apollo Hospitals, Apollo Hospitals

Language: English

Topic: Myasthenia Gravis and Thymoma

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,180