OP05.01: Impact of Doppler and gestational age on the prediction of adverse perinatal outcome in fetuses with late‐onset fetal growth restriction
Year: 2024
Type: conference-abstract
Abstract: To determine the value of gestational age (GA) and Doppler in late-onset fetal growth restriction (lateFGR) for prediction of adverse perinatal outcome (APO). Observational study on a cohort of lateFGR diagnosed at the Hospital Clínico Universidad de Chile between 2006 and 2019. The outcome was APO: a composite including ≥1 of the following: emergency Caesarean section, stillbirth, early neonatal death, perinatal asphyxia, admission to NICU and use of mechanical ventilation. Univariate and multivariate logistic regression identified variables associated with APO. A decision tree was constructed using CHAID. 495 cases of lateFGR were included. The APO rate was 20.4%. Predictors of APO were: cerebroplacental ratio (CPR) 34 weeks, the APO rate was 17.2%, while between 32–34 weeks, it was 29.1% (p = 0.003). The determination of CPR became crucial in the GA group between 32 and 34 weeks. When CPR was >p5, the APO rate was 25%, whereas < p5, it was 39.5% (p = 0.1) This study demonstrates that APO in late-onset FGR fetuses is directly related to altered CPR and gestational age at diagnosis. The use of CPR appears to have a predictive role in the late-onset FGR subgroup between 32 and 34 weeks of gestation.
DOI: 10.1002/uog.27907
Institution: Hospital Clínico de la Universidad de Chile
Language: English
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4402358488