Year: 2024
Type: conference-abstract
Abstract: Atrial septal aneurysm (ASA) is a rarely reported fetal finding. Its definition is variable, but the diagnosis is usually made when the foramen ovale flap extends at least halfway across the left atrium. It is considered a transient, self-limiting condition, but on occasion, it can be complicated by fetal arrhythmia or left ventricular (LV) inflow obstruction—if longstanding, this can lead to left heart hypoplasia. We present two cases of ASA diagnosed at the second trimester scan, one of which was subsequently complicated by LV inflow obstruction and prenatal suspicion of hypoplastic aortic arch. The progression to left heart hypoplasia in one of our cases is a good illustration of how structure fits function—a small LV preload can lead to a decreased LV output, which in turn will end up in a hypoplastic LV and hypoplastic LV outflow tract, but physiological functional changes in the newborn circulation can restore normal cardiac structure. Therefore, during prenatal counselling of suspected LV/aortic arch hypoplasia, one must keep in mind obstructive ASA as a differential diagnosis since the outcome is almost always spontaneously favourable after birth. This report is a good illustration of how structure follows function: a small LV preload can lead to a decreased LV output, which in turn will end up in a hypoplastic LV and outflow tract—all this is reversible after birth, due to the physiological circulatory modifications that occur in the newborn.
DOI: 10.1002/uog.28481
Author: C. Mandici
Institution: Grigore T. Popa University of Medicine and Pharmacy
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4402358875