Risk Factors for Serrated Polyps: Results From a Large, Multicenter Colonoscopy-Based Study
Year: 2024
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: Risk factors for serrated polyps (SPs) are not well understood. METHODS: Multivariable analyses of data from a multicenter colonoscopy-based study estimated odds ratios for having either a sessile serrated lesion or traditional serrated adenoma according to participant characteristics. RESULTS: Six thousand seventy-eighty participants were included in the analyses (565 with either a sessile serrated lesion or traditional serrated adenoma). White race was associated with a higher risk of SPs compared with Black race (adjusted odds ratio 4.64, 95% confidence interval 1.89-11.41). Obesity and current smoking were also associated with a higher risk of SPs. DISCUSSION: White race, smoking, and obesity are risk factors for precancerous SPs.
Institutions: Oregon Health & Science University, Portland VA Medical Center, New York University, University of Michigan, Michigan Medicine, University of Minnesota, Brigham and Women's Hospital, Harvard University, Dana-Farber Cancer Institute, Dana-Farber Brigham Cancer Center, The University of Texas MD Anderson Cancer Center
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G3839271222, G3890617659
OpenAlex ID: W4402363515