Clinical Characteristics and Therapeutic Management of Atopic Dermatitis in Elderly Patients Compared with Young Adult Patients: A Prospective Multicentre Study
Year: 2024
Type: article
Study design: Observational Study
Abstract: Atopic dermatitis (AD) is the most common chronic inflammatory dermatitis in developed countries, and has a major impact on those affected. Little is known about AD in elderly patients. This prospective multicentre observational study described the clinical characteristics and burden of AD in elderly subjects ≥ 65 years, as well as the therapeutic options chosen for this population in routine care, and compared findings with those in young adults with AD < 30 years. Cohort data from adult patients with moderate-to-severe AD enrolled in a French national prospective registry (December 2020 to May 2023) were analysed. Patients ≥ 65 years made up 12.5% of the total adult cohort and presented less head-and-neck and extremity involvement, and were less affected by generalized forms than young adult patients. Elderly patients predominantly had late-onset AD and had similar disease severity to younger adults. Although the overall impact of AD appeared to be lower in elderly patients and treatment was initially less used in this age group, the substantial impact on sleep and psychiatric comorbidities was similar in older and younger adult patients. Better understanding of AD in elderly patients and the establishment of age-specific treatment guidelines may help dermatologists manage the disease in older people.
Source: Acta Dermato Venereologica
Authors: Clément Pollyn-Millot, François Maccari, Jean Luc Perrot, Ziad Reguiai, Claire Boulard, Pierre André Becherel, Claire Poreaux, Laure Mery-Bossard, Domitille Beaulieu, Diane Pourchot, Anne-Claire Fougerousse, Edouard Begon, Anne-Laure Liegeon, Charlotte Fite, Inès Zaraa, Dominique Lons-Danic, Beatrice Walls, Caroline Jacobzone, Charlotte Lepelley, Daphné Denis, Guillaume Chaby
Institutions: Centre Hospitalier Universitaire Amiens-Picardie, Hôpital d'Instruction des Armées Bégin, Centre Hospitalier Universitaire de Saint-Étienne, Centre Hospitalier Intercommunal de Poissy, Centre Hospitalier Victor Dupouy, Hôpital NOVO, Centre Hospitalier Régional de Metz-Thionville, Hôpital Paris Saint-Joseph, Centre Hospitalier de Bretagne Sud
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,725
OpenAlex ID: W4402369206