Work

Impact of Chemotherapy and Hormone Therapy on Lipid Metabolism in Breast Cancer Patients: A Case Report and Literature Review

Year: 2024

Type: article

Abstract: Breast cancer has become the leading cause of cancer-related death among women, partly due to therapeutic resistance and treatment-related complications. Chemotherapy and hormone therapy play a crucial role in managing breast cancer patients, providing essential treatment for both disease control and overall survival. However, as new therapeutic approaches are introduced and life expectancy continues to increase, the use of these treatments has been associated with persistent adverse effects, including dyslipidemia. This article presents the case of a breast cancer patient treated with chemotherapy and tamoxifen-based hormone therapy who developed severe mixed dyslipidemia. It also reviews lipid metabolism alterations observed in breast cancer patients, emphasizing the importance of monitoring lipid levels in these patients, particularly those undergoing hormone therapy or chemotherapy, to prevent cardiovascular complications.

Source: Saudi Journal of Medicine

DOI: 10.36348/sjm.2024.v09i09.003

Authors: Jarnige Khadija, Kfal Youssef, El Boukhrissi Fatima, Slaoui Amal, Mahmoud Mustapha, Benbella Imane

Institutions: Centre Hospitalier Universitaire Hassan II, Sidi Mohamed Ben Abdellah University, Hôpital Militaire Moulay Ismail

Language: English

Topic: Cancer, Lipids, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402376889

FWCI:

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