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Genital lichen planus and lichen sclerosus - seemingly similar and yet different

Year: 2024
Type: article
Abstract: Genital lichen planus and lichen sclerosis are chronic autoimmune inflammatory dermatological diseases that affect both men and women.These two conditions are serious and challenging, significantly reducing the quality of daily life.Symptoms of lichen planus in both men and women include burning and painful urination, dyspareunia, as well as discharge in women.The main treatment involves topical corticosteroids, but in more severe cases, doctors may also use medications such as azathioprine, cyclophosphamide, and mycophenolate mofetil.Additionally, patients may use vaginal dilators covered with corticosteroid ointment or estrogen cream to reduce symptoms and alleviate dyspareunia.In lichen sclerosis, the symptoms are very similar.However, it's important to note that this condition increases the risk of developing cancer.Characteristic porcelain-white papules and plaques precede the onset of erythema and edema, and prolonged disease activity leads to atrophic changes and erosions.Doctors primarily treat this condition with topical corticosteroids, but they may also use cyclosporine, phototherapy, and photodynamic therapy.In men, circumcision is another form of therapy that is not uncommon.Lichen planus and genital lichen sclerosis are similar but significantly different conditions.The symptoms of both conditions are a significant problem among patients, affecting their daily lives and mental health.
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W4402379528
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