Work

Stand-alone segmentation of blood flow pulsatility measured with diffuse correlation spectroscopy

Year: 2024

Type: article

Abstract: We present a stand-alone blood flow index (BFI) pulse segmentation method for diffuse correlation spectroscopy that uses a wavelet-based representation of the BFI signal at the cardiac frequency in place of an exogenous physiological reference. We use this wavelet-based segmentation method to quantify BFI waveform morphology in a cohort of 30 healthy adults. We demonstrate that the waveform morphology features obtained with the wavelet approach strongly agree with those obtained using an exogenous blood pressure reference signal. These results suggest the promise of stand-alone wavelet-based BFI segmentation for quantifying BFI waveform morphological features.

Source: Biomedical Optics Express

DOI: 10.1364/boe.533916

Authors: Srinidhi Bharadwaj, Tara M. Urner, Kyle R. Cowdrick, Rowan O. Brothers, Tisha Boodooram, Hongting Zhao, Vidisha Goyal, Eashani Sathialingam, Yueh-Chi Wu, Ayesha Quadri, Katherine Turrentine, Mariam M. Akbar, Sydney E. Triplett, Shasha Bai, Erin M. Buckley

Institutions: Georgia Institute of Technology, Emory University, The Wallace H. Coulter Department of Biomedical Engineering, Children's Healthcare of Atlanta

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,913

Funders: National Science Foundation, Emory University, Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences

Awards: G1427448067, G1704078250, G196810821, G2289923368, G2301255353, G4134659960, G5882770475, Georgia CTSA Research Supplement to Promote Diversity in Health-Related Research (Hernandez), Diffuse optical spectroscopies to assess cerebral hemodynamics in pediatric sickle cell disease, G7415795898, Graduate Research Fellowship Program (GRFP), G7860539593

OpenAlex ID: W4402381618

FWCI: 0.229

Cites: 38

Cited by: 1

Related to: 10