Work

Stress as a possible trigger in anti–N-methyl-ᴅ-aspartate receptor encephalitis: a case series

Year: 2024

Type: article

Abstract: Anti-N-methyl-ᴅ-aspartate receptor (NMDAR) encephalitis is a rare disease with a range of neurological and psychiatric presentations. Antibodies against NMDAR receptor are purported to be pathologic, and the two known potential immunological triggers are tumors and viral infection. In half of the cases, the trigger is not known. We present two cases where stress seemed to have triggered encephalitis. These cases illustrate the possible role of stress in leading to immune dysregulation, which can lead to encephalitis. We review the role of stress in anti-NMDAR encephalitis and possible mechanisms by which stress can trigger an immune dysregulation.

Source: encephalitis

DOI: 10.47936/encephalitis.2024.00059

Authors: Sheikh Hilal Ahmad, Atif Kawoosa, Tanveer Hassan, Bashir Sanaie

Institution: Government Medical College

Language: English

Topic: Autoimmune Neurological Disorders and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402388966