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The Prospect and Challenges of Repurposing Established Drugs in Pulmonary Arterial Hypertension

Year: 2024

Type: article

Abstract: Pulmonary arterial hypertension (PAH) is a progressive disorder caused by the narrowing of small blood vessels in the lungs, which, in the absence of therapies, leads to right heart failure and premature death. No cure for this devastating disorder is known. Current management therapies aim to improve symptoms, and hence, there is a need to identify novel therapeutic interventions. The major objectives of this review are to critically evaluate current treatment strategies and highlight the challenges and prospects of established drugs and natural products for the resolution of PAH.

Source: BioChem

DOI: 10.3390/biochem4030012

Authors: Sila Ozlem Sener, Rateep Nasim, Talat Nasim

Institutions: University of Bradford, Sağlık Bilimleri Üniversitesi, University of Kent

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,137