A cutting-edge atomization-based methodology for enhancing formulation ability to resist photoaging
Year: 2024
Type: article
Study design: Clinical Trial
Abstract: Skin photoaging mainly occurs in exposed skin irradiated by ultraviolet rays from the sunlight. When exposed to ultraviolet rays, the skin will undergo certain changes to avoid damage. The inflammatory factors produced by light stimulation will induce melanocytes to produce more melanin, leading to the skin shows a rough, dark, dry, loose, and leathery appearance. In particular, when the skin is exposed to external damage and then received the damage of sunlight, such as after an aesthetic medicine treatment, it is more likely to produce post-inflammatory hyperpigmentation (PIH). However, there is a lack of a non-invasive and efficient solution. The purpose of this study is to verify a new skincare method to resist photoaging. The essence itself has a very good effect in resisting photodamage, when it through atomized to skin, it showcases a non-invasive but better-result approach to skin care. This study assessed anti-photoaging effects through in vitro (antioxidant, UVB protection, ROS tests) and human trials. In vitro results indicate the essence's efficacy. A randomized trial with 60 women (20–45 years, sensitive skin) compared atomized essence vs. smear control. After 28 days, atomized essence improved skin hydration, gloss, reduced redness, TiVi, TEWL, and UV protection. A 7-day test with Moyal Luminous Serum and Atomizer showed this skincare combo effectively prevents photodamage. Through in vitro and human experiments, we have verified that the self-developed essence itself has a very good effect of anti-photoaging. Through further comparison of human efficacy tests, we found that with the support of an atomizer, the anti-photoaging effect of the essence has been improved. Essence through atomization to resists photoaging, improves skin moisture, gloss, UV protection and reduces redness. Its non-invasive delivery ensures efficacy and user-friendliness.
Authors: Juntong Li, Shuyu Wang, Ruifang Han, Meifang Wu, Jian Zhou, Peibiao Zhao, Bin Cui
Language: English
Topic: Skin Protection and Aging
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,500
OpenAlex ID: W4402395058