Work

Discovery of Novel Non-nucleoside DOT1LR231Q Inhibitors with Improved Pharmacokinetic Properties and Anti-lung Cancer Efficacy

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c01096

Authors: Zehui Tan, Ning Guo, Shuyu Liu, Jiandong Li, Yu Chen, Jianming Cui, Hongrui Lei, Nan Jiang, Lihui Wang, Xin Zhai

Institution: Shenyang Pharmaceutical University

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Natural Science Foundation of Shenyang City, National Natural Science Foundation of China, Liaoning Revitalization Talents Program

Awards: G287425619, G5196603598, G5493386760, G8404518671

OpenAlex ID: W4402401915

FWCI: 0.417

Cites: 36

Cited by: 3

Related to: 10