Work

A case of diffused large B-cell lymphoma in an elderly patient successfully treated with R-mini-CHOP

Year: 2024

Type: article

Abstract: Diffuse large B-cell lymphoma (DLBCL) is a diverse group of B-cell lymphomas that vary in their clinical characteristics. Usually manifesting as a rapidly progressing or advanced condition, it is often curable even at advanced stages. The illness originates in extranodal and extramedullary tissues in 40% of patients. Patients over the age of 80 who have comorbidities or fragile conditions may be eligible for Rituximab and Reduced Dose CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) (R-mini-CHOP) chemoimmunotherapy. We report a 75-year-old woman with a tumor on the right side of the nose that covers the eye, so it is easy to fall out. The diagnosis of DLBCL (sinonasal) was made on the basis of computed tomography (CT) scan of the paranasal sinuses with contrast and immunohistochemical examination. Due to the age of the patient, who was included in the very elderly category with moderate frailty based on instrumental activities of daily living (IADLs), the patient was given R-mini-CHOP chemoimmunotherapy for six cycles, followed by radiation as much as 20 × 18 Gray (Gy) where the patient in the final evaluation stated complete response.

Source: Asian Journal of Oncology

DOI: 10.25259/asjo-2023-15-(477)

Authors: Faisal Syarifuddin, Wulyo Rajabto, Yayi Dwina Billianti

Institution: University of Indonesia

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402418345