Work

Conformational Differences in the Light Chain Constant Domain of Immunoglobulin G and Free Light Chain May Influence Proteolysis in AL Amyloidosis

Year: 2024

Type: article

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2024.168837

Authors: Elena S. Klimtchuk, Tatiana Prokaeva, Brian H. Spencer, Sherry Wong, Shreya Ghosh, Angela Urdaneta, Gareth Morgan, Thomas E. Wales, Olga Gursky

Institutions: Boston University, Northeastern University

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Establishing Strategies to Ameliorate Amyloid Pathology in Light Chain Amyloidosis, Apolipoprotein conformation in amyloid and cardiovascular diseases, Local dual delivery of a chemotherapy and an anti-angiogenic agent from an injectable functionalized biodegradable biomaterial system for the treatment of gliomas, Structure and Function of Serum Amyloid A in Health and Disease

OpenAlex ID: W4403908742

FWCI: 0.906

Cites: 52

Cited by: 7

Related to: 10