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Sjogren's Syndrome Presenting as Hypokalemic Paralysis- a Rare Case Presentation

Year: 2024
Type: article
Study design: Case Report
Abstract: Introduction: Sjogren's syndrome is slowly progressive protype autoimmune disease characterized by lymphocytic inltration of the exocrine glands. Most common manifestation are related to tubular dysfunction resulting from chronic interstitial nephritis and can manifest as distal renal tubular acidosis [dRTA] ,proximal RTA, tubular proteinuria and nephrogenic diabetes inspidus of which RTA is the main clinical manifestation. It is more common in middle aged women and two thirds of them will develop symptoms Hypokalemic paralysis rarely occurs as the rst manifestation of renal tubule disorder due to pSS. Case Report: A 30 year old female presented to casualty of hind institute of medical sciences, sitapur, uttar Pradesh. With complains of all four limbs weakness which is acute in onset. Patient also gives history of similar complains 15 days back and was diagnosed hypokalaemia and was given potassium correction and symptomatic treatment and discharged with advice of oral potassium supplement which she discontinued after discharge . Conclusion: We report this case to highlight the fact that patients presenting with hypokalaemia periodic paralysis can be due to early sjogren's syndrome which might not present with typical sicca symptoms and dryness of mouth, enlargement of parotid gland, which needs to be investigated and started on appropriate line of management.
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4402459411
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