Work

Lighting the way forward: using resonance Raman spectroscopy to non-invasively assess tissue perfusion

Year: 2024

Type: article

Abstract: Poor tissue perfusion is an important driver of shock in patients after surgery, trauma, and sepsis.1 Assessment of tissue oxygenation and volume status in these patients involves assimilating multiple endpoints of resuscitation.2 This commonly includes measuring surrogate markers such as serum lactate and central venous oxygenation (ScVO2) through blood sampling. These data points are helpful in guiding treatment, but they can only offer intermittent insights when limited by the frequency of blood draws. In the case of ScVO2, they can also require invasive procedures such as central line placement which carries risks of infection, pneumothorax, and thrombosis.

Source: Trauma Surgery & Acute Care Open

DOI: 10.1136/tsaco-2024-001600

Authors: Chavi Rehani, Rosemary Kozar

Language: English

Topic: Spectroscopy Techniques in Biomedical and Chemical Research

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,100

OpenAlex ID: W4402474042