Work

Assessment of Volumetric Changes Using Megavoltage-Cone Beam Computed Tomography (MV-CBCT) for Adaptive Radiotherapy in Head and Neck Cancer: A Case Series

Year: 2024

Type: article

Abstract: Intensity-modulated radiation therapy (IMRT) has brought about interest in adaptive radiotherapy (ART) due to its benefit of accurately prescribing doses to tumors and sparing normal critical organs. Critical dosimetric errors and geometrical misses can occur due to anatomical changes during radiotherapy. In the present study, five patients with head and neck malignancies undergoing radiation therapy were assessed for changes in primary gross tumor volume (GTVp), nodal gross tumor volume (GTVn), and clinical target volume-high risk (CTV-HR) using weekly megavoltage-cone beam computed tomography (MV-CBCT) scans. All patients had a reduction in GTV and lateral neck diameter (LND). There were reductions in tumor volumes leading to re-planning in the 20th fraction. Daily CBCT can guide the decision on the need for adaptation in patients with tumor volume reduction and with volumes going outside the body.

Source: Cureus

DOI: 10.7759/cureus.69251

Authors: Atokali Chophy, Sweety Gupta, Deepa Joseph, Swati Verma, Manoj Gupta

Institution: All India Institute of Medical Sciences Rishikesh

Language: English

Topic: Advanced Radiotherapy Techniques

Subfield: Radiation

Field: Physics and Astronomy

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402492949