Work

Artificial gravity: an effective countermeasure for microgravity-induced headward fluid shift?

Year: 2024

Type: article

Abstract: Brief exposure to continuous or intermittent artificial gravity via short-arm centrifugation was insufficient in mitigating the intracranial pathophysiological effects of the headward fluid shift simulated during head-down tilt bed rest (HDTBR). Our results suggest that greater centrifugation session duration, gravitational force, or both may be required to prevent the development of spaceflight-associated neuro-ocular syndrome and should be considered in future ground-based countermeasure studies.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00441.2024

Authors: Larry A. Kramer, Khader M. Hasan, Xu Zhang, Edwin Mulder, Darius A. Gerlach, Karina Marshall-Goebel, Brandon R. Macias, Steven S. Laurie, Gary Strangman, Raj Iyer, Eric M. Bershad

Institutions: The University of Texas Health Science Center at Houston, Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR), National Aeronautics and Space Administration, Johnson Space Center, KBR (United States), Harvard University, Massachusetts General Hospital, Baylor College of Medicine

Language: English

Topic: Spaceflight effects on biology

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Aeronautics and Space Administration, Deutsches Zentrum für Luft- und Raumfahrt, National Center for Advancing Translational Sciences

Awards: G486457145, G6342610676

OpenAlex ID: W4402493783

FWCI: 1.435

Cites: 41

Cited by: 6

Related to: 10