Work

2,2,3,3,4,4,4-Heptafluorobutyl Acetate: Transesterification Reaction of 2,2,3,3,4,4,4-Heptafluoro-1-Butanol and Isopropyl Acetate—Side-Product Composition

Year: 2024

Type: conference-paper

Abstract: As the object of investigation in the present study, reactive distillation based on the transesterification of isopropyl acetate (IPAc) and 2,2,3,3,4,4,4-heptafluorobutanol (HFBol) under acidic conditions is addressed. This process aims to obtain 2,2,3,3,4,4,4-heptafluorobutyl acetate (HFBAc), which is used in the production of non-aqueous electrolytes, ethyllithium sulphate, charge retention medium, ultraviolet light-absorbing oligomers, etc. Through a combination of NMR spectroscopy and GC-MS, it was determined that during the process, the following were primarily formed in the system: target HFBAc and the by-product, isopropanol. The following side-products were identified: di-isopropyl ether, acetic acid, water, and 2,2,3,3,4,4,4-heptafluorobutyl isopropyl ether (HFB-IPEth). No bis(1H,1H-heptafluorobutyl) ether or acetic anhydride were identified in the system. For HFBol, HFBAc and HFB-IPEth the 1H, 19F and 13C{19F}), 19F-19F COSY NMR, and mass spectra were reported in this study.

Source: International Electronic Conference on Processes (ECP)

DOI: 10.3390/engproc2024067040

Authors: Andrei V. Polkovnichenko, Evgeniya I. Kovaleva, Nikita A. Selivanov, Tatiana D. Ksenofontova, Sergey Ya. Kvashnin, Egor V. Lupachev

Institution: NS Kurnakova Institute of General and Inorganic Chemistry

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: hybrid

Funder: Russian Science Foundation

Award: G7867453158