Work

Influence of the Eliminated Ligand Structure on the Reduction Rate of the Cobalt(III) Complexes

Year: 2024

Type: article

Abstract: The reduction of the heteroleptic cobalt(III) complexes with bipyridine ligands of different structures of the model drug molecule is studied by in situ NMR spectroscopy. The nature of the ligand eliminated during reduction is shown to exert a substantial effect on the reduction rate, which indicates that an optimum amount of cobalt should be chosen for the redox-activated delivery of a certain drug.

Source: Координационная химия

DOI: 10.31857/s0132344x24040039

Authors: I. A. Nikovskii, K. A. Spiridonov, A. A. Dan′shina, E. A. Khakina, Yu. V. Nelyubina

Institutions: Russian Academy of Sciences, A. N. Nesmeyanov Institute of Organoelement Compounds, Lomonosov Moscow State University, Moscow Institute of Physics and Technology

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

OpenAlex ID: W4402501762

FWCI:

Cites: 17

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Related to: 10