Work

Development of Novel Indole-Based Covalent Inhibitors of TEAD as Potential Antiliver Cancer Agents

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c00925

Authors: Chen Zhou, Chunbao Sun, Wei Zhou, Tian Tian, Daniel C. Schultz, Tong Wu, Mu Yu, Lizi Wu, Liya Pi, Chenglong Li

Institutions: University of Florida, Tulane University, UF Health Cancer Center

Language: English

Topic: Hippo pathway signaling and YAP/TAZ

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Science Foundation, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, Congressionally Directed Medical Research Programs, State of Florida

Awards: G1138554163, Acquisition of a Q Exactive HF Hybrid Quadrupole-Orbitrap, G4944093634, National High Magnetic Field Laboratory Renewal 2023-2027, Acquisition of timsTOF Pro for Complex Lipidomic Analyses, Developing YAP/TEAD Inhibitors for Novel NASH-Associated Hepatocellular Carcinoma Therapeutics

OpenAlex ID: W4402503958

FWCI: 2.272

Cites: 74

Cited by: 12

Related to: 10