Work

Systems mapping of bidirectional endosomal transport through the crowded cell

Year: 2024

Type: article

Abstract: and become competent for endosomal capture and minus-end movement in collaboration with membrane-associated Rab7-RILP. We show that endosomes surf over the ER through the crowded cell and move bidirectionally under the control of MAPs for motor activation and through motor replacement and capture by endosomal anchors.

Source: Current Biology

DOI: 10.1016/j.cub.2024.08.026

Authors: Marlieke L.M. Jongsma, Nina Bakker, Lenard M. Voortman, Roman I. Koning, Erik Bos, Jimmy J.L.L. Akkermans, Lennert Janssen, Jacques Neefjes

Institutions: Leiden University Medical Center, Leiden University

Language: English

Topic: Cellular transport and secretion

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $7,030

Funders: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, European Research Council, H2020 European Research Council

Awards: G3079932233, G6211653225

OpenAlex ID: W4402515327

FWCI: 2.263

Cites: 109

Cited by: 12

Related to: 10