Development of Organocatalytic Darzens Reactions Exploiting the Cyclopropenimine Superbase
Year: 2024
Type: article
Abstract: -epoxy carbonyl compounds in good yields was developed taking advantage of the high basic strength and low nucleophilicity of cyclopropenimine superbases. The catalytic active free base can easily be generated in situ from its hydrochloride salt and maintained in the active deprotonated form by performing the reactions in a heterogeneous reaction system in the presence of excess potassium carbonate as a sacrificial base.
Source: Molecules
Authors: Carmine Lops, Lucia Pasquato, Paolo Pengo
Institution: University of Trieste
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,069
OpenAlex ID: W4402524294