A Novel Validation Study of a Wrist Orthosis for the Objective Evaluation of Rigidity in Parkinson’s Disease
Year: 2024
Type: article
Abstract: Parkinson’s disease (PD) is a neurological condition affecting millions, marked by mobility issues and characterized by motor and non-motor symptoms, including tremors, bradykinesia, postural instability, and rigidity. Diagnosis often relies on subjective assessments such as the Movement Disorder Society Unified PD Rating Scale (MDS-UPDRS). This study focuses on validating a wrist orthosis designed to quantify rigidity in PD patients objectively. Developed at the Center for Innovation and Technological Evaluation in Health (NIATS), the orthosis integrates a Faulhaber linear motor (LM 2070-080-11) and microcontroller (MCLM 3006 S RS). Calibration experiments, including varied mass assessments, established the orthosis’s reliability. Results indicated a newly calculated force constant of 14.28 N/A, 18.49% higher than the manufacturer’s value, with a strong Pearson correlation coefficient (0.9997189). The orthosis detected masses ranging from 39.07 to 812.64 grams without yielding. Angular displacement calibration, utilizing a GP10 goniometer and Myosystem-Br1 software, demonstrated linearity, supported by Pearson coefficients of 0.9995091 and 0.995259. These findings underscore the orthosis’s potential as a reliable tool for measuring rigidity in PD patients, promising advancements in physiotherapy and disease monitoring.
Authors: Caio Tonus Ribeiro, Daniel Hilário da Silva, Leandro Rodrigues da Silva Souza, José Renato Munari Nardo, Adriano Alves Pereira
Institutions: Universidade Federal de Uberlândia, Instituto Federal Goiano
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $312
OpenAlex ID: W4402525740