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Angiosarcoma of the breast gland: molecular genetic profile, diagnosis and treatment

Year: 2024

Type: article

Abstract: Angiosarcoma is a rare, aggressive tumor arising from the endothelial cells of blood vessels that can affect internal organs, but the most common location is the skin. The article presents current data on the molecular genetic profile, diagnosis and treatment of primary and secondary angiosarcomas of the breast. A search for relevant sources was carried out in the PubMed, Cochrane Library and eLibrary systems, publications from 2012 to 2023 were examined, 29 of which were used to write this review.no standard treatment guidelines, and the optimal approach remains surgical resection to achieve negative resection margins. The role of neoadjuvant, adjuvant chemotherapy and radiotherapy remains controversial.

Source: Bone and soft tissue sarcomas tumors of the skin

DOI: 10.17650/2219-4614-2024-16-3-55-60

Authors: L. N. Lyubchenko, E. K. Saribekyan, A. R. Bosieva, A. D. Zikiryakhodzhaev, G. L. Buchkin, N. D. Zamaldinov, A. A. Fedenko

Institutions: Ministry of Health of the Russian Federation, Medical Radiological Research Center, P.A. Hertzen Moscow Oncology Research Institute, Peoples' Friendship University of Russia, Sechenov University

Language: English

Topic: Vascular Tumors and Angiosarcomas

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4402527622

FWCI:

Cites: 27

Cited by:

Related to: 10