Work

A ganglioglioma versus a schwannoma: Which is in the sacral spine?

Year: 2024

Type: article

Abstract: INTRODUCTION AND IMPORTANCE: Sacral spinal gangliogliomas, rare WHO grade I tumors, present a surgical challenge due to their proximity to critical nerve roots. Symptoms often include lower back pain, sciatica, and bladder dysfunction. Diagnosis is confirmed through MRI and biopsy, with surgical resection being the primary treatment. CASE PRESENTATION: A 66-year-old woman presented with left lower limb pain and weakness. MRI showed an intradural lesion at the left S1 root. She underwent surgery, resulting in near-total tumor resection. Postoperatively, she was pain-free and ambulatory. Pathology confirmed a ganglioglioma. CLINICAL DISCUSSION: Initially suspected as a disc herniation, MRI indicated a schwannoma-like lesion, but surgery and pathology revealed a ganglioglioma. Total resection was challenging due to the tumor's neural adherence. Radiotherapy and chemotherapy are generally not used for low-grade gangliogliomas. CONCLUSION: Treating sacral spinal gangliogliomas requires precise surgery and a multidisciplinary approach. Accurate diagnosis and careful planning are essential for minimizing neurological risks and improving patient outcomes. Continued research is crucial for advancing treatment strategies.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2024.110269

Authors: Ali Msheik, Elie Fahed, Delivrance Sebaaly, Gerard Abadjian, Philippe Younes

Institutions: Lebanese University, Lebanese Hospital Geitaoui-University Medical Center

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,800