Effect of the flow-force relationships used in two parameter modelling of freezing and vitrification protocols for bovine embryos
Year: 2024
Type: article
Abstract: in 5 vol% glycerol was small. Also the effect on shrinking and swelling in vitrification media was small, but the original 2P model predicted stronger swelling of embryos during one-step CPA removal. One variant that we compared simply assumes Raoult's law, i.e. M = m, even in very concentrated solutions We conclude that this simple model is easy and appropriate for simulating osmotic events of embryos. But if a method for correcting for the deviation from Raoult's law is used, a symmetrical model seems more appropriate than the original (asymmetrical) 2P model.
Source: Cryobiology
Author: H. Woelders
Institution: Wageningen University & Research
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,670
Awards: G1135209311, G3878183228, G5190465091
OpenAlex ID: W4402533786
