Early maturation of neural auditory novelty detection − Typical development with no major effects of dyslexia risk or music intervention
Year: 2024
Type: article
Abstract: OBJECTIVE: To determine the early development of novelty detection and the effect of familial dyslexia risk and infant music intervention on this development. METHODS: In the longitudinal DyslexiaBaby study, we investigated the maturation of novelty-P3 and late-discriminative negativity (LDN) event-related potentials to novel sounds at birth (N = 177) and at the ages of 6 (N = 83) and 28 months (N = 131). RESULTS: Novelty-P3 was elicited at all ages, whereas LDN was elicited at 6 and 28 months. Novelty-P3 amplitude was largest at 6 months, and its latency decreased with age. LDN amplitude decreased and latency increased between 6 to 28 months. Dyslexia risk or intervention had no effects, apart from a longer LDN latency in the high-risk than no-risk group. CONCLUSIONS: Already neonates respond to novel environmental sounds, indicating prerequisites for detecting potentially relevant events at birth. Maturation influences neural novelty detection. SIGNIFICANCE: Novelty detection is crucial for perceiving important events, but its early development has been scarcely studied. We found, with a large sample, that neonates detect novel events, and showed the developmental pattern of its neural signature. The results serve as a reference for studies on typical and atypical novelty-detection development in infancy when behavioral testing is challenging.
Source: Clinical Neurophysiology
Authors: T. Kujala, V. Putkinen, P. Virtala
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,590
OpenAlex ID: W4402540098