Method Development and Stress Degradation Profile of Umifenovir by UV Spectrophotometry
Year: 2024
Type: article
Abstract: A simple, selective, and economical UV spectrophotometric method has been developed using ethanol as solvent (50%) to determine the umifenovir content in bulk and pharmaceutical dosage formulations. At a pre-determined λ max of 260 nm, it has shown linear in the 10-50 µg/mL range and exhibited a good correlation coefficient (R2 = 0.9927) and excellent mean recovery (98.00–104%). The method was validated statistically, and recovery studies were done for linearity, precision, and accuracy. The obtained results proved that the method can be employed for the routine analysis of umifenovir in bulks and commercial formulations. Keywords: UV spectrophotometry, Umifenovir, Validation, Method development, Stress Degradation
Authors: R. B. Nalanda, Gudimella Ramya Priya, Abdulrahaman Horan
Institution: GITAM University
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4402552937