Work

Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure

Year: 2024

Type: article

Abstract: To address the effect of cardiac cachexia on the failing heart, we analyzed serial home-care monitoring of the rate–pressure product, as substitution of myocardial oxygen consumption, over 218 days in a 79-year-old man with a catecholamine-dependent end-stage dilated cardiomyopathy. At the end of his home-care visits, his body weight decreased to 37 kg from 55.2 kg (baseline). We found a linear reduction of the rate–pressure product accompanied by weight loss (r2 = 0.186; P = 0.0001), implying the progression of cardiac cachexia as a possible role in reducing myocardial oxygen consumption, which would mitigate energy deprivation of the failing heart.

Source: Annals of Internal Medicine Clinical Cases

DOI: 10.7326/aimcc.2023.1465

Authors: Makoto Suzuki, Manami Kishimoto, Tomomi Horita, Akira Fujii, Satoru Hamada

Language: English

Topic: Heart Failure Treatment and Management

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402558697

FWCI:

Cites: 11

Cited by:

Related to: 10