Work

Indium-Mediated Preparation of Bis(α-hydroxyallenes) or α,α′-Dihydroxyallenynes and Further Gold-Catalyzed Cyclizations

Year: 2024

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide We present the regio- and diastereoselective Barbier-type allenylation reaction of glyoxals mediated by indium to furnish highly valuable syn -bis(α-hydroxyallenes) and syn -α,α′-dihydroxyallenynes. The gold-catalyzed controlled cyclization of these unsaturated diols enables the divergent preparation of three types of oxacycles.

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.4c01648

Authors: Teresa Martínez del Campo, Daniel San Martín, Laura Gamarra, Eva Cerrón, Sara Cembellín, Hikaru Yanai, Pedro Almendros

Institutions: Universidad Complutense de Madrid, Consejo Superior de Investigaciones Científicas, Tokyo University of Pharmacy and Life Sciences, Instituto de Química Orgánica General

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: Universidad Complutense de Madrid, Ministerio de Ciencia e Innovación, Japan Society for the Promotion of Science, Agencia Estatal de Investigación

Awards: G1175115578, G2262748287, G2390397592, G2689240055, G300979063, Development of functional molecules bearing stable carbanion moieties, G34346518, G3480869486, G425668148, G4526231891, G4534730369, G5080475149, G5584235085, G586857820, G6557789269, G7084143925, G7434936867, 古代説話における諸寺縁起の研究

OpenAlex ID: W4402567359

FWCI: 0.565

Cites: 18

Cited by: 4

Related to: 10