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Cytogenetic abnormality in non‐systemic light chain amyloidosis monoclonal gammopathy of renal significance: A field needs to be explored

Year: 2024

Type: article

Abstract: The role of cytogenetic abnormalities in non-systemic light chain amyloidosis monoclonal gammopathy of renal significance diseases still needs to be clarified. Bhutani et al. present the results of a study investigating the underlying plasma cell cytogenetic abnormalities in monoclonal immunoglobulin deposition disease (MIDD). The results show that translocation (11;14) is a common abnormality in MIDD and affects the presentation and outcomes. Commentary on: Bhutani et al. Translocation (11;14) is a common cytogenetic abnormality in clonal plasma cells in monoclonal immunoglobulin deposition disease. Br J Haematol 2024; 205:1860-1865.

Source: British Journal of Haematology

DOI: 10.1111/bjh.19768

Author: Xianghua Huang

Institutions: Nanjing General Hospital of Nanjing Military Command, Nanjing University

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Natural Science Foundation of China