Work

Access to ( E )- N ′-benzylidene- N -(2-(phenylsulfonyl)ethyl)acetohydrazide via C(sp 2 )−H activation and reduction of ( E )- N ′-benzylideneacetohydrazide with (vinylsulfonyl)benzene

Year: 2024

Type: article

Abstract: A novel route for C(sp 3 )-N bond formation via C(sp 2 )−H activation/reduction by metal-free which uses ( E)- N′-benzylideneacetohydrazide and (vinylsulfonyl)benzene to synthesize derivatives of ( E)- N′-benzylidene- N-(2-(phenylsulfonyl)ethyl)acetohydrazide has been reported. This methodology features good functional group tolerance and convenient operation. In addition, it uses inexpensive and insensitive chemical reagents as raw materials and provides an atom- and efficient method for the preparation of ( E)- N′-benzylidene- N-(2-(phenylsulfonyl)ethyl)acetohydrazides.

Source: Journal of Chemical Research

DOI: 10.1177/17475198241275297

Authors: Haiyang Wang, Fusheng Liu

Institutions: Qingdao University of Science and Technology, Shandong First Medical University

Language: English

Topic: Catalytic C–H Functionalization Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,100

Funder: Shandong First Medical University