Work

Photochemical Defluorinative Alkenylation of Trifluoromethyl Alkenes with Organoboronic Acids

Year: 2024

Type: article

Abstract: We have developed a photo‐catalyzed defluorinative two‐component coupling reaction of trifluoromethyl alkenes and organoboronic acids, providing a straightforward and efficient route for the synthesis of functionalized gem‐difluorinated 1,4‐dienes. Both the chemical yields and functional group tolerance are generally good.

Source: European Journal of Organic Chemistry

DOI: 10.1002/ejoc.202400973

Authors: Shiyu He, Bo Xu

Institution: Donghua University

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: bronze

Funder: National Natural Science Foundation of China

Award: 对有机合成反应中的紧密离子对的系统研究