Work

Epinephrine infusion as an adjuvant treatment for breakthrough reactions during desensitization to methotrexate

Year: 2024

Type: article

Abstract: Desensitization protocols can induce temporary tolerance to a drug which has previously caused an allergic response, and thus facilitate appropriate and timely medical management.1 Rapid desensitization protocols have proven safe and cost-effective; in the context of cancer treatment, desensitization can allow patients to remain on first-line therapy, which can improve morbidity and survival.2 Breakthrough allergic reactions are frequent during desensitization, but tend to remit during subsequent procedures.

Source: World Allergy Organization Journal

DOI: 10.1016/j.waojou.2024.100965

Authors: Carla Toledo-Salinas, David Alejandro Mendoza-Hernandez, Paul J. Turner

Institutions: Instituto Nacional de Pediatria, Imperial College London

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,640