Work

Development of silicone-based phantoms for biomedical optics from 400 to 1550 nm

Year: 2024

Type: article

Abstract: This work describes the development of silicone-based evaluation phantoms for biomedical optics in the wavelength range from 400 to 1550 nm. The absorption coefficient μa and the reduced scattering coefficient μs′ were determined using an integrating sphere setup. Zirconium dioxide pigments were used as scatterers and carbon black as absorbers. We developed an in-house manufacturing process using a Hauschild SpeedMixer to ensure reproducibility. A set of nine cubic phantoms with three different reduced scattering and absorption coefficients was produced. Prediction of the μa and μs′ was done by using the weighted mass concentrations of the used materials. The average prediction accuracy over all wavelengths and phantoms is 1.0% for the reduced scattering coefficient and 3.5% for the absorption coefficient.

Source: Biomedical Optics Express

DOI: 10.1364/boe.533481

Authors: Markus Wagner, Oliver Fugger, Florian Foschum, Alwin Kienle

Institutions: Universität Ulm, Institute for Laser Technology in Medicine and Measurement Technique

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $1,913

Funder: Bundesministerium für Bildung und Forschung