Work

Paediatric perioperative hypersensitivity: the performance of the current consensus formula and the effect of uneventful anaesthesia on serum tryptase. Reply to BJA Open 2024; 12: 100307

Year: 2024

Type: article

Abstract: Editor—It was with great interest that we read the response by Green and colleagues1 to our publication on tryptase in paediatric hypersensitivity.2 We would like to thank the authors for their prompt response to our request for external validation of the new paediatric consensus formula for mast cell activation. Some aspects of their validation study and our original study warrant further discussion. Although the Australian cohort is smaller than the cohort in our previous study (38 vs 190 patients with paired acute and baseline tryptase sampling), it significantly strengthens the validity of our conclusion, both in terms of numerical representation and geographical distribution.

Source: BJA Open

DOI: 10.1016/j.bjao.2024.100308

Authors: Nils Vlaeminck, Marie-Line van der Poorten, Vera Saldien, Vito Sabato, Didier G. Ebo

Institutions: University of Antwerp, Antwerp University Hospital

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,870