Work

Possibility of Measuring of Erythrocyte Size Distribution Parameters by Laser Diffractometry of a Blood Smear

Year: 2024

Type: article

Abstract: We consider the issues of obtaining information about the distribution of red blood cells in size from the scattering pattern of a laser beam on a wet blood smear. Within this article it is assumed to calculate the first three moments of the size distribution. The analytical model of light diffraction by blood smears was developed, as well as numerical experiments for verification suggested approach were carried out. The possibility of calculating average diameter of erythrocyte, width and asymmetry of size distribution by analyzing the angular distribution of light intensity in the diffraction pattern was shown

Source: Journal of Biomedical Photonics & Engineering

DOI: 10.18287/jbpe24.10.040302

Authors: Sergey Yu. Nikitin, Evgeniy G. Tsybrov, Maria S. Lebedeva, Andrei E. Lugovtsov, Alexander V. Priezzhev

Institution: Lomonosov Moscow State University

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: diamond

Funders: Moscow Center of Fundamental and Applied Mathematics, Ministry of Education and Science of the Russian Federation, Russian Science Foundation

Awards: G1064708086, G3839204104, G8155917183