Cerebellopontine angle craniopharyngioma in familial adenomatous polyposis
Year: 2024
Type: article
Study design: Case Report
Abstract: Background: Craniopharyngiomas are benign tumors arising in the sellar and suprasellar regions. Although ectopic tumors do occur, it is usually due to local spread or recurrent tumors. Purely ectopic cerebellopontine angle (CPA) or 4th ventricle tumors are extremely rare and have been found to be significantly associated with familial adenomatous polyposis (FAP), a genetic disorder. Case Description: Only four cases of ectopic CPA craniopharyngioma associated with FAP have been reported to date. Here, we present the 5th case of ectopic CPA craniopharyngioma on a background of FAP. The previously described cases have been elaborated as well. Conclusion: CPA tumor with a background of FAP should raise a differential diagnosis of craniopharyngioma, and similarly, a CPA primary ectopic craniopharyngioma may raise suspicion of underlying APC gene mutation.
Source: Surgical Neurology International
Authors: Sayantan Bose, James Balogun, Daniel du Plessis, Matthew Bailey, Fiona Lalloo, Omar Pathmanaban
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4402691450