Work

Enhancing diabetic foot ulcer healing: Impact of the regulation of the FUS and ILF2 RNA‑binding proteins through negative pressure wound therapy

Year: 2024

Type: article

Abstract: , the knockdown of FUS and ILF2 significantly reduced the rate of skin wound healing in diabetic mice. The results of the present study therefore provide new insights into the mechanism by which NPWT promotes DFU wound healing. In conclusion, the RBPs, FUS and ILF2, promoted DFU wound healing by regulating the function of keratinocytes and reducing the inflammatory response and oxidative stress.

Source: International Journal of Molecular Medicine

DOI: 10.3892/ijmm.2024.5427

Authors: Ying Tang, Hua Ji, Yanyan Yan, Die Hu, Murong Xu, Min Xu, Xiaotong Zhao, Mingwei Chen

Institutions: Anhui Medical University, First Affiliated Hospital of Anhui Medical University

Language: English

Topic: Wound Healing and Treatments

Subfield: Rehabilitation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4402697866

FWCI: 0.682

Cites: 80

Cited by: 5

Related to: 10