Work

Light-chain amyloidosis with dysphagia as the main symptom: a case report

Year: 2024
Type: article
Study design: Case Report
Abstract: BACKGROUND: Immunoglobulin light-chain amyloidosis is a relatively rare condition with a worldwide incidence of 5.1-12.8 cases per million person-years (Baker, 2022). It is characterized by a clonal population of immunoglobulin-secreting cells that produce a monoclonal light chain of κ or λ type as either an intact molecule or a fragment. CASE PRESENTATION: A 69-year-old East Asian (Chinese) male patient who presented with progressive dysphagia visited multiple hospitals repeatedly for more than 2 years and was finally diagnosed with immunoglobulin light-chain amyloidosis. CONCLUSIONS: Otolaryngologists should consider immunoglobulin light-chain amyloidosis when encountering suspicious clinical manifestations and intervene early to avoid misdiagnosis.
Language: English
Open Access status: gold
Estimated APC paid: $2,790
OpenAlex ID: W4402697915
FWCI: 0.118
Cites: 10
Cited by: 1
Related to: 10