Work

A green, cheap and robust method for selective hydrogenation of nitroarenes

Year: 2024

Type: article

Abstract: A commercially available nickel was utilized as an effective catalyst for the exclusive hydrogenation of nitroarenes to primary anilines in gram-scale without additional column chromatographic purification. This novel synthetic hydrogenation strategy features wide substrate scope, mild conditions and operational simplicity in aqueous media at room temperature . Further transformations resulted in the delivery of important amine-containing drugs and pharmaceutical intermediates.

Source: Tetrahedron

DOI: 10.1016/j.tet.2024.134269

Authors: Piao Ding, Eman Fayad, Ola A. Abu Ali, Hua-Li Qin

Institutions: Wuhan University of Technology, Taif University

Language: English

Topic: Nanomaterials for catalytic reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,500

Funders: National Natural Science Foundation of China, Taif University, Wuhan University of Technology