Work

Strategies and Tactics for Site Specific Deuterium Incorporation at Each Available Carbon Atom of α-Pinene

Year: 2024

Type: article

Abstract: The development of several unique strategies and tactics for the synthesis of α-pinene isotopologues that has culminated in access to all eight possible isomers with deuterium incorporated selectively at each available carbon atom is described. Access to this library of isotopologues provides new tools to more fully investigate the atmospheric autoxidation of α-pinene, a complex process that plays a major role in the formation of secondary organic aerosol in the Earth's atmosphere.

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.4c01702

Authors: Jingyi Luo, Mary Alice Upshur, Marvin Vega, Nicolle A. Doering, Jonathan Varelas, Zhouyang Ren, Franz M. Geiger, Richmond Sarpong, Regan J. Thomson

Institutions: Northwestern University, University of California, Berkeley

Language: English

Topic: Chemical Reactions and Isotopes

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, National Institute of General Medical Sciences, Division of Chemistry, National Science Foundation Graduate Research Fellowship Program

Awards: Collaborative Research: Isotopologue Synthesis and Use for Elucidating Important Chemical Mechanisms of Organic Condensation Reactions in Atmospheric Particles, Surfaces of Secondary Organic Aerosol Particles, G6915139076, G754063543, Renewal: Strategies and Methods for Complex Molecule Synthesis, G993257700

OpenAlex ID: W4402720813

FWCI: 0.437

Cites: 57

Cited by: 3

Related to: 10