Year: 2024
Type: article
Study design: Observational Study
Abstract: Introduction: Although patients with idiopathic hypersomnia (IH) may have executive and attentional deficits related to sleepiness, they often seem cleverly expressed during outpatient clinic and less disturbed about achieving their academic and professional goals than patients with narcolepsy.However, unlike narcolepsy, their intellectual abilities have not been studied.A recent study suggested that one third of children with narcolepsy have high intellectual potential.We therefore measured the intellectual quotient (IQ) in adults with narcolepsy type 1, IH and controls.Method: The groups included 30 patients with IH, 30 patients with narcolepsy type 1 and 30 healthy paid controls, all matched to the IH group for age, sex and educational level.IQ was measured using the Weschler Adult Intelligence Scale IV which includes four indices, including the Verbal Comprehension Index, the Perceptual Reasoning Index, the Working Memory Index, and the Processing Speed Index.Results: The mean age in the IH group was 33.4 ± 11 years (23 women; Epworth sleepiness score: 14.4 ± 4.3), in the narcolepsy group 31.2 ± 12.5 years (21 women; Epworth score: 16.9 ± 4.8) and in the control group 33.1 ± 9.3 years (23 women, Epworth score: 5 ± 3.8).Performance on the Full Scale IQ and each index was better in the IH group than in the narcolepsy group, and did not differ from the control group.Patients with IH performed better on the visual puzzle subtest than adults with narcolepsy and controls.Conclusion: Patients with IH have better abilities than people with narcolepsy (and sometimes controls) to perceive, analyze, synthesize, and think with visual materials, including visuospatial processing and mental rotation abilities (which are not influenced by executive function).Whether this is related to milder level of sleepiness, latter onset of the disease or genuine abilities remains to be determined.
Source: Journal of Sleep Research
DOI: 10.1111/jsr.14293
Authors: Although patients with idiopathic hypersomnia (IH) may have executive and attentional deficits related to sleepiness, they often seem cleverly expressed during outpatient clinic and less disturbed about achieving their academic and professional goals than patients with narcolepsy. However, unlike narcolepsy, their intellectual abilities have not been studied. A recent study suggested that one third of children with narcolepsy have high intellectual potential. We therefore measured the intellectual quotient (IQ) in adults with narcolepsy type 1, IH and controls.
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Award: G4605665620
OpenAlex ID: W4402724871